A Better Way To DNA

When budgets tighten and stability matters, leading biotech companies are choosing A Better Way to DNA with Novel Bio. We are a U.S. vendor delivering scalable plasmid DNA production and design services with speed, efficiency, and scientific expertise. 

What We Offer

Accelerating plasmid DNA innovation across synthetic biology and therapeutic development

For decades, the world’s labs have relied on E. coli to make plasmid DNA. But its limitations have created a DNA bottleneck—slowing discovery and leaving countless medicines stranded on the R&D shelf. Novel Bio exists to change that.

Whether you’re designing novel constructs for synthetic biology or preparing plasmid DNA for GMP mRNA manufacturing, we help you move faster from idea to outcome. Acting as an extension of your team, we streamline complex plasmid design and scale DNA production with speed, precision, and flexibility.

Our PhD-level scientists—trained alongside the inventors of modern cloning techniques like Gibson Assembly—bring deep technical fluency and bench experience to every project. From early-stage research to regulated therapeutic development, we remove the DNA bottlenecks that slow innovation.

We Deliver:

  • Competent cells and media for RUO cloning

  • Custom plasmid design and assembly

  • Plasmid DNA production services

  • Analytical services

How It Works

The NBx Platform™

We use our NBx Platform, among other technology, to make plasmid DNA with higher yield, faster growth, and better quality than today’s systems. Our NBx platform and services are fully compatible with existing workflows, delivering:

  • High-quality plasmid DNA (pDNA)

  • Accelerated production timelines

  • Fewer costly production failures

  • Support for pioneering first-in-class therapies

The NBx CyClone™ (Early Access May ‘25)

Now you can have the power of NBx in your very own lab. Take the stress out of DNA cloning and alleviate your biggest pain points by creating chemically competent cells. Our Cyclone product offers:

  • Speed - 3x faster workflows than E. coli

  • Complexity - Maintain sequence motifs E. coli can’t handle

  • Superior yield & quality - Get more out of your R&D

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What’s Next

Who We Are

We are DNA
Experts. Problem Solvers. Artists. Entrepreneurs.

We set out to overcome the DNA bottleneck that keeps genetic medicines from patients. With our unique expertise in DNA, we believe we solve this fundamental problem and contribute to biotech in a big way.

Use Cases

  • Custom vector development

  • Large plasmid construction (>100 kbp)

  • Plasmid DNA purification

  • Pharmaceutical drug development

  • Gene and cell therapy

  • Nucleic acid vaccines

  • mRNA manufacturing and therapeutics

  • And more